Anti-Plaque Potential of Lime (Citrus Aurantifolia) Peel Essential Oil: A Scoping Review

Sri Mulyanti, Euis Julaeha, Yaya Rukayadi, Amaliya Amaliya
https://www.jidmr.com/journal/wp-content/uploads/2024/09/58-D24_3118_Amaliya_Amaliya_Indonesia-Rev.pdf

Abstract

During the last decades, a huge body of evidence has been accumulated suggesting that citrus fruits and their constituents might have a role in preventing many diseases including oral disease. We aimed to map the existing evidence of the potential of Citrus aurantifolia essential oil as an antiplaque agent. Electronic databases (PUBMED, Google Scholar, and Scopus) were searched using the broad MeSH terms and keywords. Search terms included Citrus aurantifolia, lime peel, essential oil, and antiplaque. The last search was performed on October 15th, 2023. Only original articles evaluating the potential of lime peel essential oil in plaque-forming inhibition were included. Study selection and systematic review were carried out following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Review (PRISMA- ScR) statement. Before the beginning of the review, the Authors defined a checklist for inclusion criteria, thus including articles that meet the following: (i) published on peer- reviewed scientific journals; (ii) Citrus aurantifolia; (iii) essential oil derived from Citrus aurantifolia peel; (iv) preclinical and clinical studies. Reviews, meta-analyses, conference abstracts, and book chapters were excluded. Four reviewers performed the extraction of articles. Out of 6430 records, 1980 were screened for titles and abstracts after the removal of duplicates, only 59 were considered to be potentially eligible for inclusion. Finally, only 4 articles were included. The result showed that Citrus aurantifolia peel essential oil indirectly prevents the formation of dental plaque by inhibiting the oral growth of bacteria initiating the formation of biofilms.

Keywords:

Anti-plaque; Lime; Peel; Essential oil